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October 23, 2011

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December 10, 2011

Tricyclic antidepressants, carbamazepine, mexiletine, gabapentin, mild opioid analgesics and isosorbide dinitrate spray are often effective in controlling

the effects of isosorbide dinitrate (ISDN), a NO donor with local vasodilating properties, in spray form in the management of chronic neuropathic pain.

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March 11, 2012

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Isosorbide dinitrate spray 30 mg per day administered at bedtime. Class I study ( n = 1): 18% more pain reduction compared to placebo. Not evaluated, Not

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Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray: a double-blind placebo-controlled cross-over study. Yuen KC, Baker NR,

August 8, 2011

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February 6, 2012

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Treatment of Chronic Painful Diabetic Neuropathy With Isosorbide Dinitrate Spray. A double-blind placebo-controlled cross-over study. Kevin C.J. Yuen, MRCP1

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January 3, 2012

Glyceryl trinitrate patches as an alternative to isosorbide dinitrate spray in the treatment of chronic painful diabetic neuropathy.(Observations)

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September 27, 2011

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October 17, 2011

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October 13, 2011

Nitrates come as tablets, capsules, patches and sprays. Common types are glyceryl trinitrate (GTN), isosorbide mononitrate and isosorbide dinitrate. There are

Treatment of diabetic neuropathy with isosorbide dinitrate spray 174. NO-based therapies for migraine 175. NO-based therapy for fibromyalgia

Glyceryl trinitrate patches as an alternative to isosorbide dinitrate spray in the treatment of chronic painful diabetic neuropathy. Rayman G, Baker NR, Krishnan

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March 11, 2012

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January 2, 2012

Local application of isosorbide dinitrate spray seems to be effective in relieving overall pain and burning discomfort. Yuen et al49 evaluated the

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Increased exercise tolerance and reduced duration of ischemia after isosorbide dinitrate oral spray in angina pectoris. Am J Cardiol. 1988 Mar 25;61(9):4E-6E.

April 1, 2012

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Topicals: Capsaicin cream and isosorbide dinitrate spray. A pilot study of isosorbide dinitrate spray for diabetic neuropathy demonstrated safety and efficacy in

September 6, 2011

Treatment of diabetic neuropathy with isosorbide dinitrate spray 172. NO-based therapies for migraine 173. NO-based therapy for fibromyalgia

Topical agents such as capsaicin cream and isosorbide dinitrate spray can provide effective local pain control. Any of these medications may

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October 24, 2011

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October 19, 2011

To evaluate the possibility of improving clinical practice in the treatment of angina pectoris, the duration of relief of pain with isosorbide dinitrate

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